- A Case of Hepatocelluar Carcinoma Mimicking Focal Nodular Hyperplasia
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Eui Ju Park, Jae Young Jang, Soung Won Jeong, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Hong Soo Kim, Boo Sung Kim, So Young Jin, Ji Young Hwang
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Journal of the Korean Liver Cancer Study Group. 2014;14(1):53-59. Published online March 31, 2014
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DOI: https://doi.org/10.17998/jlc.14.1.53
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Abstract
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- Recently, detection of an incidental hepatic tumor has rapidly increased with the introduction
of multi-modality imaging techniques. And then, it is very important to determine whether
these tumors are malignant or benign lesions. In some cases, differentiation from other hepatic
tumors such as focal nodular hyperplasia or hepatic adenoma and hepatocellular carcinoma
can be extremely difficult, both clinical and radiologic finding. Therefore, it is suggested that
combination of multi-modality imaging study than using only a single imaging test. Despite
advanced imaging studies such as computed tomography (CT), magnetic resonance imaging
(MRI), contrast enhanced ultrasonography, and positron emission tomography (PET) showed
a high sensitivity and specificity, role of liver biopsy is still remained to confirm the diagnosis.
The use of liver biopsy in the diagnosis of hypervascular hepatic tumors is controversial.
However if the tumors was shown rapid growth tendency and heterogeneous radiological
appearance, liver biopsy or surgical resection should be considered to provide final diagnosis
and prompt curative treatment. We report a case of a hepatocelluar carcinoma showing
similar radiologic characteristics to focal nodular hyperplasia in patients without high risk
factors of hepatocelluar carcinoma.
- A Case of Early Hepatocellular Carcinoma with High Grade Dysplastic Nodule
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Jae Young Jang , Yun Soo Kim, Young Kuk Cheon, Young Seok Kim, Jong Ho Moon, Young Deok Cho, So Young Jin, Chan Sup Shim, Boo Seong Kim
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Journal of the Korean Liver Cancer Study Group. 2002;2(1):105-108. Published online July 31, 2002
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Abstract
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- A 47-year-old male was referred for evaluation of a hepatic nodular lesion incidentally found on routine check up. He had no history of previous liver disease. Physical examination revealed no abonormality. Laboratory findings showed that HBsAG and anti-HCV were negative. Serum AST was minimally elevated and serum AFP was within normal range. Abdominal ultrasonogram showed a 1.3 cm-sized, hypoechoic nodule with peripheral halo in segment 5 of liver. Spiral CT revealed a well enhancing nodule in arterial phase, which could not be detected in portal and delayed phase. Liver biopsy showed well-differenciated hepatocellular carcinoma on the background of high grade dysplastic nodule. Surgical resection was recommended, however he refused and discharged.
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